Iran lashed out at the United States and Europe Wednesday as Israel looked to retaliate against the Islamic Republic for its missile attack and the region braced for the possibility of a third confrontation between the two arch-foes.

“In our region, the root cause of problems, which leads to conflicts, wars, concerns and hostilities and such like, results from the presence of the same people who claim to advocate peace and tranquillity in the region; that is America and some European countries,” Iran’s Supreme Leader Ayatollah Seyyed Ali Khamenei said Wednesday in Tehran, according to the Iranian Press TV.

He accused the United States and the West of helping Israel with financial, logistical, and intelligence support as it battled Iranian proxy groups over the last year, such as Hamas in Gaza, Hezbollah in Lebanon, and the Houthis in Yemen.